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The dataset generation failed because of a cast error
Error code:   DatasetGenerationCastError
Exception:    DatasetGenerationCastError
Message:      An error occurred while generating the dataset

All the data files must have the same columns, but at some point there are 1 new columns ({'07_48_88_1_1_1_1_1_1_1_1_1'}) and 1 missing columns ({'CELL_1'}).

This happened while the csv dataset builder was generating data using

hf://datasets/altoslabs/perturbench/jiang24_split.csv (at revision c3150b8c6ca086beb1110e9b7da0a77814c01f5b)

Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)
Traceback:    Traceback (most recent call last):
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/builder.py", line 1831, in _prepare_split_single
                  writer.write_table(table)
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/arrow_writer.py", line 714, in write_table
                  pa_table = table_cast(pa_table, self._schema)
                             ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/table.py", line 2272, in table_cast
                  return cast_table_to_schema(table, schema)
                         ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/table.py", line 2218, in cast_table_to_schema
                  raise CastError(
              datasets.table.CastError: Couldn't cast
              07_48_88_1_1_1_1_1_1_1_1_1: string
              train: string
              -- schema metadata --
              pandas: '{"index_columns": [{"kind": "range", "name": null, "start": 0, "' + 525
              to
              {'CELL_1': Value('string'), 'train': Value('string')}
              because column names don't match
              
              During handling of the above exception, another exception occurred:
              
              Traceback (most recent call last):
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1450, in compute_config_parquet_and_info_response
                  parquet_operations, partial, estimated_dataset_info = stream_convert_to_parquet(
                                                                        ^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 993, in stream_convert_to_parquet
                  builder._prepare_split(
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/builder.py", line 1702, in _prepare_split
                  for job_id, done, content in self._prepare_split_single(
                                               ^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/builder.py", line 1833, in _prepare_split_single
                  raise DatasetGenerationCastError.from_cast_error(
              datasets.exceptions.DatasetGenerationCastError: An error occurred while generating the dataset
              
              All the data files must have the same columns, but at some point there are 1 new columns ({'07_48_88_1_1_1_1_1_1_1_1_1'}) and 1 missing columns ({'CELL_1'}).
              
              This happened while the csv dataset builder was generating data using
              
              hf://datasets/altoslabs/perturbench/jiang24_split.csv (at revision c3150b8c6ca086beb1110e9b7da0a77814c01f5b)
              
              Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)

Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.

CELL_1
string
train
string
CELL_2
train
CELL_3
train
CELL_4
train
CELL_5
train
CELL_6
train
CELL_7
train
CELL_8
train
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train
CELL_10
train
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train
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CELL_100
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CELL_101
train
End of preview.

The dataset contains data used in work: "Perturbench: Benchmarking machine learning models for cellular perturbation analysis."

The data comes from the following publications:

  • Norman, T. M., Horlbeck, M. A., Replogle, J. M., Ge, A. Y., Xu, A., Jost, M., Gilbert, L. A., and Weissman, J. S. (2019). Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science, 365(6455):786–793.
  • Srivatsan, S. R., McFaline-Figueroa, J. L., Ramani, V., Saunders, L., Cao, J., Packer, J., Pliner, H. A., Jackson, D. L., Daza, R. M., Christiansen, L., Zhang, F., Steemers, F., Shendure, J., and Trapnell, C. (2020). Massively multiplex chemical transcriptomics at single-cell resolution. Science, 367(6473):45–51.
  • Frangieh, C. J., Melms, J. C., Thakore, P. I., Geiger-Schuller, K. R., Ho, P., Luoma, A. M., Cleary, B., Jerby-Arnon, L., Malu, S., Cuoco, M. S., Zhao, M., Ager, C. R., Rogava, M., Hovey, L., Rotem, A., Bernatchez, C., Wucherpfennig, K. W., Johnson, B. E., Rozenblatt-Rosen, O., Schadendorf, D., Regev, A., and Izar, B. (2021). Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion. Nat. Genet., 53(3):332–341.
  • Jiang, L., Dalgarno, C., Papalexi, E., Mascio, I., Wessels, H.-H., Yun, H., Iremadze, N., Lithwick Yanai, G., Lipson, D., and Satija, R. (2024a). Systematic reconstruction of molecular pathway signatures using scalable single-cell perturbation screens. bioRxiv, page 2024.01.29.576933.
  • McFaline-Figueroa, J. L., Srivatsan, S., Hill, A. J., Gasperini, M., Jackson, D. L., Saunders, L., Domcke, S., Regalado, S. G., Lazarchuck, P., Alvarez, S., et al. (2024). Multiplex single cell chemical genomics reveals the kinase dependence of the response to targeted therapy. Cell Genomics, 4(2)
  • Szałata, A., Benz, A., Cannoodt, R., Cortes, M., Fong, J., Kuppasani, S., Lieberman, R., Liu, T., Mas-Rosario, J. A., Meinl, R., Nourisa, J., Tumiel, J., Tunjic, T. M., Wang, M., Weber, N., Zhao, H., Anchang, B., Theis, F. J., Luecken, M. D., Burkhardt, D. B. (2024). A benchmark for prediction of transcriptomic responses to chemical perturbations across cell types. NeurIPS, (38).

Datasets with fixed splits have their splits included as .csv files with two colums: the first corresponds to the cell ID (which is the .obs_names of the respective h5ad file) and second to the split value (train, val, test). Some datasets contain multiple splits in which case the split files are in a tar.gz.

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